| Electronic Detection Platform |
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The detection and analysis is performed electronically without expensive and delicate optical components.
The presence of a specific target is detected on the disposable cartridge and analyzed by a robust electronic reader. Ohmx’s detection technology relies on the production of an electrochemically active product, which in turn generates a self-calibated electrocatalytic signal on the electrode. The bioelectronic signal consisting of energy and current levels is measured at the electrode and is directly correlated to the concentration of the target being analyzed in the sample.
Each electrode of the sensor’s array is presented with a mixed monolayer of the sensing element that has the following key features:
- A molecular wire that anchors it to the electrode and is used to shuttle electrons
- A redox active metal complex, whose signal is measured after sample addition
- A specific probe moiety that dictates the assay construct. This probe may consist of a self--immolative group that works in conjunction with standard immunoassay approaches or a group with scissile bonds recognized specifically by different target proteases.
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